7 Results for "

NGF/bNGF

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "NGF/bNGF" in MCE Product Catalog:

Cat. No.: HY-P990474
Synonyms: AS2886401-00

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

Anti-NGF/bNGF Antibody is a CHO-expressed humanized antibody that targets NGF/bNGF. Anti-NGF/bNGF Antibody has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.14 kDa. The isotype control for Anti-NGF/bNGF Antibody can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P991711
CAS No.: 2975573-74-9
Povovetug is a humanized IgG1κ chimeric monoclonal antibody inhibitor targeting NGF/bNGF. Povovetug has a significant analgesic activity. Povovetug can be used for central neuroinflammation like chronic radicular pain research .
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Cat. No.: HY-P991324

Research Areas:  

Inflammation/Immunology

MEDI-7352 is a human bispecific antibody (bsAb) targeting NGF/bNGF & TNF. MEDI-7352 can be used in osteoarthritis (OA) pain research .
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Cat. No.: HY-P991325

Target:  

Trk Receptor

Research Areas:  

Inflammation/Immunology

CRB-0089 is a human monoclonal antibody (mAb) targeting NGF/bNGF. CRB-0089 can be used in analgesia research.
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Cat. No.: HY-P991323

Research Areas:  

Inflammation/Immunology

MEDI-1912 is a human monoclonal antibody (mAb) targeting NGF/bNGF. MEDI-1912 inhibits signaling through TrkA and p75 receptors. MEDI-1912 can be used in chronic pain research .
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Cat. No.: HY-P992345

Target:  

Trk Receptor

Research Areas:  

Neurological Disease

DS002 is a human monoclonal antibody targeting NGF/bNGF, with an IC50 of 6.60 nM against human NGF, 1.98 nM against rat NGF, and 8.46 nM against mouse NGF. DS002 blocks NGF-TrkA binding, interrupts pain signal transduction, inhibits TrkA-mediated downstream signaling pathways, and alters aromatic amino acid metabolic pathways. DS002 inhibits cancer cell proliferation. DS002 exerts a preventive effect on Paclitaxel-, Cisplatin- and Vincristine-induced peripheral neuropathy in rats. DS002 can be used in studies related to chronic pain and chemotherapy-induced peripheral neuropathy .
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Cat. No.: HY-P990629

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

MEDI-578 is a CHO-expressed human antibody that targets NGF/bNGF. MEDI-578 has a huIgG2a heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for MEDI-578 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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