1 Result for "

NMS 293

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NMS 293" in MCE Product Catalog:

Cat. No.: HY-168979
CAS No.: 1606995-47-4
Synonyms: NMS-03305293; NMS-293
Target:  

PARP

Research Areas:  

Cancer

Itareparib (NMS-03305293; NMS-293) is a selective, orally active, blood-brain barrier-permeable PARP1 inhibitor with an IC50 < 0.01 μM. Itareparib does not form PARP1-DNA trapping complexes, avoids PARP-DNA "retention", reduces PAR levels and inhibits the growth of homologous recombination-deficient cells. Itareparib can be used in research on advanced solid tumors, recurrent gliomas and other conditions .
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