1 Result for "

NN8828

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NN8828" in MCE Product Catalog:

Cat. No.: HY-P991271
Synonyms: NNC-114-0005; NN9828; NNC01140006
NN-8828 (NNC-114-0005; NN9828; NNC01140006) is a human IgG1 monoclonal antibody inhibitor targeting IL-21 that binds and neutralizes soluble IL-21 with a Kd of 0.19 pM. NN-8828 restores the balance between effector T cells and regulatory T cells, inhibits pathological antibody production, and alleviates IL-21-mediated inflammatory responses without inducing antibody-dependent cellular cytotoxicity. NN-8828 exhibits favorable biosafety. NN-8828 can be used in research related to rheumatoid arthritis, type 1 diabetes, and systemic lupus erythematosus .
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