1 Result for "

NP-10679

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NP-10679" in MCE Product Catalog:

Cat. No.: HY-148825
Purity:  99.42%
NP10679 is a selective, pH dependent GluN2B subunit-specific N-methyl-D-aspartate (NMDA) receptor inhibitor with high oral bioavailability and good brain penetration. NP10679 inhibits GluN2B with IC50s of 23 and 142 nM at pH 6.9 and 7.6, respectively. NP10679 is a histamine H1 antagonist and a hERG channel inhibitor with IC50s of 73 and 620 nM, respectively. NP10679 is a reversible inhibitor of human liver CYP enzymes .
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