1 Result for "

NSC-286193

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NSC-286193" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-114570
CAS No.: 60084-10-8
Purity:  99.84%
Synonyms: NSC 286193; Riboxamide
Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH). Tiazofurin enhances the autosecretion of IL-6 in K562 cells. Tiazofurin also has anti-orthopoxvirus and anti-variola activities. Tiazofurin can be used for the study of leukemia and lung cancer .
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