1 Result for "

NSC204855

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NSC204855" in MCE Product Catalog:

Cat. No.: HY-N8470
CAS No.: 54526-94-2
Synonyms: NSC 204855; U 40615
Target:  

Bacterial

Research Areas:  

Infection

Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC50=2.19 μM).
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