1 Result for "

NUCC555

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NUCC555" in MCE Product Catalog:

Cat. No.: HY-122179
CAS No.: 1060469-90-0
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

NUCC-555 is an activin antagonist. NUCC-555 interacts with Trp25, Trp28, Phe55, Tyr93, Lys103, and Asn107 in the Activin A binding pocket. NUCC-555 blocks Activin A-mediated hepatic stellate cells (HSCs) activation. NUCC-555 promotes liver regeneration and halts fibrosis progression in chronic liver disease models. NUCC-555 inhibits Activin A-mediated ovarian cell proliferation. NUCC-555 decreases FSH levels in ovariectomized mice .
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