2 Results for "

NVS-SM2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "NVS-SM2" in MCE Product Catalog:

Cat. No.: HY-111520
CAS No.: 1562333-92-9
Purity:  99.15%
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease

NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research [2].
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Cat. No.: HY-111520R
CAS No.: 1562333-92-9
NVS-SM2 (Standard) is the analytical standard of NVS-SM2 (HY-111520). This product is intended for research and analytical applications. NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research [2].
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