3 Results for "

Nav1.2/β

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Nav1.2/β" in MCE Product Catalog:

Cat. No.: HY-P5811
Synonyms: CcoTx1; β-TRTX-cm1a
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Ceratotoxin-1 (CcoTx1), a peptide toxin, is an voltage-gated sodium channel subtypes inhibitor. Ceratotoxin-1 inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Ceratotoxin-1 also inhibits Nav1.8/β1 .
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Cat. No.: HY-170930
Research Areas:  

Neurological Disease

Anticonvulsant agent 9 (compound 4f) is an α1β2γ2 GABAA receptors activator. Anticonvulsant agent 9 activatesα1β2γ2 GABAA receptors with an EC50 of 1.24 μM. Anticonvulsant agent 9 inhibits the inactivation of Nav1.2 channels. Anticonvulsant agent 9 exhibits significant anticonvulsant activities .
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Cat. No.: HY-P5810
CAS No.: 880885-98-3
Synonyms: CcoTx2; β-TRTX-cm1b
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively .
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