2 Results for "

OD1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "OD1" in MCE Product Catalog:

Cat. No.: HY-P1443
Target:  

Sodium Channel

Research Areas:  

Cancer

OD1 is a scorpion α-toxin that can be isolated from the venom of the Iranian yellow scorpion (Odonthobuthus doriae. OD1 is a modulator of mammalian Nav1.7 (EC50: 4.5 nM) [1] .
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Cat. No.: HY-P5900
Synonyms: m3-HwTx-IV
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

m3-Huwentoxin IV (m3-HwTx-IV) is a potent NaV inhibitor with IC50s of 3.3, 6.8, 7.2, 8.4, 11.9 and 369 nM against hNaV1.7, hNaV1.6, hNaV1.3, hNaV1.1, hNaV1.2 and hNaV1.4, respectively in QPatch assay. m3-Huwentoxin IV dose-dependently suppresses spontaneous pain induced by the NaV1.7 activator OD1 in a rodent pain model [1].
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