2 Results for "

ONC392

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ONC392" in MCE Product Catalog:

Cat. No.: HY-P990042
CAS No.: 2226344-78-9
Synonyms: ONC-392; BNT 316

Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology Cancer

Gotistobart (ONC-392; BNT 316) is a humanized anti-CTLA-4 antibody with selective regulatory T cell depletion activity in the tumor microenvironment. Gotistobart can be used for the research of cancer, such as non-small cell lung cancer .
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Cat. No.: HY-P992177

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

AI-025 is an anti-PD-1 antibody. AI-061, a combination formulation of AI-025 and ONC-392 (HY-P990042), inhibits the downregulation of cell activation and proliferation mediated by PD-1 and CTLA-4, thereby restoring immune function and activating cytotoxic T lymphocyte-mediated immune responses against tumor cells. AI-025 can be used in cancer research .
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