1 Result for "

ONT 093

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ONT 093" in MCE Product Catalog:

Cat. No.: HY-15134
CAS No.: 216227-54-2
Purity:  99.21%
Synonyms: OC 144-093; OC 144093
Target:  

P-glycoprotein

Research Areas:  

Infection Cancer

ONT-093 (OC 144-093) is a potent and orally active inhibitor of P-glycoprotein pump. ONT-093 inhibits P-gp-mediated ATPase activity with an IC50 of 0.16 μM. ONT-093 can inhibit drug efflux and increase bioavailability. ONT-093 reverses cancer cells multidrug resistance to chemotherapeutic drugs. ONT-093 can be used for the researches of cancer and infection, such as colon cancer and malarial .
loading...
    loading...