1 Result for "

P2L-003

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "P2L-003" in MCE Product Catalog:

Cat. No.: HY-180244
CAS No.: 1359416-20-8
Research Areas:  

Cancer

P2L-003 is a selective PAR2 antagonist with an IC50 of 0.62 μM in HT-29 cells. P2L-003 blocks PAR2-mediated Ca 2+ mobilization without affecting PAR1, PAR4, or ATP-mediated signaling and dose-dependently suppresses the downstream MAPK signaling cascades, including ERK1/2 and p38 phosphorylation. P2L-003 can be used for colon cancer research .
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