2 Results for "

PARP-mediated

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PARP-mediated" in MCE Product Catalog:

106
106 Cited Publications
Cat. No.: HY-16106
CAS No.: 1207456-01-6
Synonyms: BMN-673; LT-673
Target:  

PARP

Research Areas:  

Cancer

Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity .
loading...
    loading...
Cat. No.: HY-16106A
CAS No.: 1207456-00-5
Synonyms: (8R,9S)-BMN-673; (8R,9S)-LT-673
Target:  

PARP

Research Areas:  

Cancer

(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC50 of 144 nM .
loading...
    loading...