3 Results for "

PDGFR-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "PDGFR-IN-2" in MCE Product Catalog:

Cat. No.: HY-42933
CAS No.: 190728-25-7
Target:  

PDGFR

Research Areas:  

Cardiovascular Disease

PDGFR-IN-2 (Compound 16C) is a 4-phenoxyquinoline derivative. PDGFR-IN-2 is a platelet-derived growth factor receptor (PDGFr) inhibitor (IC50: 0.20 μM). PDGFR-IN-2 inhibits the activity of PDGFr tyrosine kinase .
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Cat. No.: HY-13342AS
CAS No.: 2468771-43-7
Purity:  92.56%
Synonyms: YN968D1-d8 free base
Apatinib-d8 (free base) is the deuterium labeled Apatinib free base . Apatinib free base (YN968D1 free base) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 (IC50=1 nM). Apatinib free base (YN968D1 free base) is an anti-angiogenic drug for the research of advanced or metastatic gastric cancer. Apatinib free base (YN968D1 free base) potently inhibits Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. It also inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFRβ .
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Cat. No.: HY-163471
Target:  

PDGFR VEGFR

Research Areas:  

Cancer

PDGFRα/β/VEGFR-2-IN-1 (6f), a multiple PDGFRα/ and VEGFR-2 tyrosine kinase inhibitor, particularly targets PDGFRα, PDGFRβ, and VEGFR-2 kinases with Nano molar concentrations .
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