2 Results for "

PF00734200

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PF00734200" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-10287
CAS No.: 869490-23-3
Purity:  99.83%
Synonyms: PF-00734200; PF-734200
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

Gosogliptin is a potent and selective inhibitor of dipeptidyl peptidase-IV (DPP-IV).
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Cat. No.: HY-10287A
CAS No.: 869490-47-1
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

Gosogliptin hydrochloride is the hydrochloride of Gosogliptin (HY-10287). Gosogliptin (PF-00734200) is a potent, orally active, selective, and competitive inhibitor of DPP-IV, the enzyme mainly responsible for the degradation of the incretin peptides GLP-1 and glucose-dependent insulinotropic polypeptide. Gosogliptin demonstrates rapid and reversible inhibition of plasma DPP-4 activity. Gosogliptin stimulates insulin secretion and improves glucose tolerance .
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