1 Result for "

PF04577806

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PF04577806" in MCE Product Catalog:

Cat. No.: HY-139467
CAS No.: 1072100-81-2
Target:  

SHP2 PKC

Research Areas:  

Metabolic Disease

PF-04577806 is a potent, selective and ATP competitive PKC inhibitor. PF-04577806 shows potent inhibitory activity towards PKCα, PKCβI, PKCβII, PKCγ, and PKCθ with IC50s of 2.4 nM, 8.1 nM, 6.9 nM, 45.9 nM, and 29.5 nM, respectively. PF-04577806 can reverse retinal vascular leakage in diabetic rats .
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