1 Result for "

PF6274484

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PF6274484" in MCE Product Catalog:

Cat. No.: HY-101450
CAS No.: 1035638-91-5
Purity:  98.76%
Target:  

EGFR

Research Areas:  

Cancer

PF-6274484 is a potent EGFR inhibitor with Kis of 0.14 nM and 0.18 nM for EGFR-L858R/T790M and WT EGFR, respectively. PF-6274484 inhibits EGFR-L858R/T790M autophosphorylation in H1975 tumor cells and EGFR WT in A549 tumor cells with IC50s of 6.6 and 5.8 nM, respectively .
loading...
    loading...