1 Result for "

PGD97

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PGD97" in MCE Product Catalog:

Cat. No.: HY-P10226
CAS No.: 2717490-36-1
Target:  

Chloride Channel CFTR

Research Areas:  

Endocrinology

PGD97 is a selective cyclic peptide inhibitor against CAL/CFTR interactions, with a KD value of 6 nM towards the CAL PDZ domain for its desulfide cyclized form. PGD97 (desulfide cyclized form) has selectivity ≥ 130-fold compared to NHERF1/2 PDZ domains. PGD97 is capable of stabilizing F508del-CFTR at the cell membrane and improving CFTR function required for proper fluid homeostasis in tne lung. PGD97 can be used for the research of cystic fibrosis .
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