1 Result for "

PHA680626

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "PHA680626" in MCE Product Catalog:

Cat. No.: HY-125090
CAS No.: 398493-74-8
PHA-680626 is an effective inhibitor of the interaction between Aurora-A and N-Myc. PHA-680626 inhibits kinase activity of AURKA and Bcr-Abl, and induces N-Myc degradation. PHA-680626 decreases phosphorylation of CrkL and histone H3. PHA-680626 shows anti-proliferative and pro-apoptotic activity on Imatinib (HY-15463)-resistant chronic myeloid leukemia cell lines and primary CD34+ cells .
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