1 Result for "

PK68

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PK68" in MCE Product Catalog:

Cat. No.: HY-128348
CAS No.: 2173556-69-7
Purity:  99.92%
Target:  

RIP kinase

Research Areas:  

Inflammation/Immunology Cancer

PK68 is a potent orally active and specifical type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and can be used for the research of inflammatory disorders and cancer metastasis .
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