19 Results for "

PTGS

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "PTGS" in MCE Product Catalog:

3
3 Cited Publications
Art. -Nr.: HY-P80091
Synonyms: PTGS2; COX 2; COX2; COX-2; Cyclooxygenase; Cyclooxygenase2; Cyclooxygenase-2; hCox 2; PGG/HS; PGH synthase 2; PGHS 2; PGHS2; PHS 2; PHS II; PHS2 ; Prostaglandin endoperoxide synthase 2; Prostaglandin G/H synthase 2 precursor; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; TIS10II; PGH2_HUMAN.

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

1
1 Cited Publications
Art. -Nr.: HY-N6929
CAS. Nr.: 565-63-9
Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
Art. -Nr.: HY-163897
CAS. Nr.: 3098187-24-4
PROTAC NCOA4 degrader-1 is a VHL-based PROTAC NCOA4 degrader. PROTAC NCOA4 degrader-1 is a ferroptosis inhibitor. PROTAC NCOA4 degrader-1 reduces Fe 2+ elevation, ROS production, MDA content and PTGS2 mRNA expression. PROTAC NCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model. PROTAC NCOA4 degrader-1 can be used for the researches of inflammation and immunology .
Art. -Nr.: HY-150586
CAS. Nr.: 2494082-34-5
Target:  

HDAC Apoptosis

Forschungsgebiete:  

Cancer

PTG-0861 is a selective histone deacetylase 6 (HDAC6) inhibitor with the IC50 value of 5.92 nM. PTG-0861 induces apoptosis and can be used in the study of acute myeloid leukemia, multiple myeloma and other hematological cancers .
Art. -Nr.: HY-175813
CAS. Nr.: 3113770-74-1
NPSR1 antagonist-1 is a potent and peripherally restricted neuropeptide S receptor 1 (NPSR1) antagonist. NPSR1 antagonist-1 can inhibit IL-6, PTGS2, IL-20, and CXCL8 expression. NPSR1 antagonist-1 can reduce TNF-α cytokine levels. NPSR1 antagonist-1 can be used for the research of inflammation, such as peritonitis .
Art. -Nr.: HY-N6929R
CAS. Nr.: 565-63-9
Angelic acid (Standard)) is the analytical standard of Angelic acid (HY-N6929). This product is intended for research and analytical applications. Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
Art. -Nr.: HY-RS11392
Forschungsgebiete:  

Others

PTGS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PTGS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-RS11393
Forschungsgebiete:  

Others

PTGS2 Human Pre-designed siRNA Set A contains three designed siRNAs for PTGS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-121025
CAS. Nr.: 23000-46-6
Reinheit:  99.65%
Target:  

TGF-β Receptor

Forschungsgebiete:  

Others

BUR1 is a BMP upregulator (EC50: 98 nM) and activates BMPRII signalling. BUR1 induces BMP2 and PTGS2 expression. BUR1 reversed pulmonary arterial pressure in Monocrotaline (HY-N0750) induced rats .
Art. -Nr.: HY-RS16902
Forschungsgebiete:  

Others

Ptgs2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptgs2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-RS19231
Forschungsgebiete:  

Others

Ptgs1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptgs1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-RS23344
Forschungsgebiete:  

Others

Ptgs2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptgs2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-RS25720
Forschungsgebiete:  

Others

Ptgs1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptgs1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-N19877
CAS. Nr.: 123828-59-1
Neokadsuranic acid B is a 14 (13→12)-seco-lanostane-type triterpenoid acid that exists in the stems of Kadsura longipedunculata and Radix Aconiti Lateralis Preparata. It has high binding affinity for PTGS2 (COX-2). Neokadsuranic acid B shows promise for research into rheumatoid arthritis .
Art. -Nr.: HY-P84274
Synonyms: COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

Art. -Nr.: HY-P84274A
Synonyms: COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

Art. -Nr.: HY-P82792
Synonyms: PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

Art. -Nr.: HY-P82792A
Synonyms: PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

Art. -Nr.: HY-P85939
Synonyms: COX 2; COX-2; COX2; Cyclooxygenase 2; Cyclooxygenase 2b; Cyclooxygenase; Cyclooxygenase-2; Cyclooxygenase2; fj02a10; Glucocorticoid-regulated inflammatory cyclooxygenase; Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase; GRIPGHS; hCox 2; Macrophage activation-associated marker protein P71/73; OTTHUMP00000033524; PES-2; PGG/HS; PGH synthase 2; PGH2_HUMAN; PGHS 2; PGHS-2; PGHS2; PHS 2; PHS II; PHS2; Prostaglandin endoperoxide synthase 2; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin endoperoxide synthase 2; Prostaglandin G/H synthase 2; Prostaglandin G/H synthase 2 precursor; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin G/H synthase; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin-endoperoxide synthase 2; PTGS2; PTGS2a; TIS10; TIS10 protein; unp1239; wu:fj02a10

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

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