2494082-34-5
2494082-34-5
Chemical Structure
PTG-0861
- CAS No.: 2494082-34-5
- Formula:C15H9F5N2O3
- Molecular Weight:360.24
IUPAC Name: 2,3,4,5,6-pentafluoro-N-(4-(hydroxycarbamoyl)benzyl)benzamide
InChIKey: KMHKOOKREYIIBC-UHFFFAOYSA-N
SMILES: O=C(NCC1=CC=C(C(NO)=O)C=C1)C2=C(F)C(F)=C(F)C(F)=C2F
Biological Activity: PTG-0861 is a selective histone deacetylase 6 (HDAC6) inhibitor with the IC50 value of 5.92 nM. PTG-0861 induces apoptosis and can be used in the study of acute myeloid leukemia, multiple myeloma and other hematological cancers[1].
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PTG-0861 | PTG-0861 is a selective histone deacetylase 6 (HDAC6) inhibitor with the IC50 value of 5.92 nM. PTG-0861 induces apoptosis and can be used in the study of acute myeloid leukemia, multiple myeloma and other hematological cancers. | |||||||||||||||||||||
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