3113770-74-1
Chemical Structure
NPSR1 antagonist-1
- CAS No.: 3113770-74-1
- Formula:C30H42F2N4O2
- Molecular Weight:528.68
IUPAC Name: N-((4,4-difluoro-1-(4-methylpiperazin-1-yl)cyclohexyl)methyl)-N-((1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)cyclohexanecarboxamide
InChIKey: CQPRANBLBXEONM-UHFFFAOYSA-N
SMILES: O=C(C1CCCCC1)N(CC2(N3CCN(C)CC3)CCC(F)(F)CC2)CC4=CC5=C(N(C)C4=O)C=CC=C5
Biological Activity: NPSR1 antagonist-1 is a potent and peripherally restricted neuropeptide S receptor 1 (NPSR1) antagonist. NPSR1 antagonist-1 can inhibit IL-6, PTGS2, IL-20, and CXCL8 expression. NPSR1 antagonist-1 can reduce TNF-α cytokine levels. NPSR1 antagonist-1 can be used for the research of inflammation, such as peritonitis[1].
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NPSR1 antagonist-1 | NPSR1 antagonist-1 is a potent and peripherally restricted neuropeptide S receptor 1 (NPSR1) antagonist. NPSR1 antagonist-1 can inhibit IL-6, PTGS2, IL-20, and CXCL8 expression. NPSR1 antagonist-1 can reduce TNF-α cytokine levels. NPSR1 antagonist-1 can be used for the research of inflammation, such as peritonitis. | |||||||||||||||||||||
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Keywords
