2 Results for "

PTP1B-IN-17

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PTP1B-IN-17" in MCE Product Catalog:

Cat. No.: HY-144718
CAS No.: 2848581-85-9
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

PTP1B-IN-17 (Compound 45), a potential selective benzimidazole derivative, acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 30.2 μM. PTP1B-IN-17 can be used for the research of type 2 diabetes.
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Cat. No.: HY-162499
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

MY17 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50=0.41±0.05 μM). MY17 alleviates palmitic acid (PA) -induced insulin resistance by up-regulating the expression of phosphorylated insulin receptor substrate (IRS1) and protein kinase B (AKT). By binding with PTP1B, MY17 can inhibit the activity of PTP1B, thereby improving insulin signaling and having anti-diabetic activity. MY17 can be used in the study of type 2 diabetes .
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