1 Result for "

PX20350

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PX20350" in MCE Product Catalog:

Cat. No.: HY-139418
CAS No.: 1198085-23-2
Target:  

FXR

Research Areas:  

Cancer

PX20350 is a FXR agonist with EC50s of 83 and 10 nM for mFXR and hFXR, respectively. PX20350 significantly induces NDRG2 mRNA expression. PX20350 potently reduces liver tumor cells (SK-GI-18 cells) growth and metastasis, and has anti-tumorigenic activity in orthotopic xenograft mouse models .
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