1 Result for "

PY314

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PY314" in MCE Product Catalog:

Cat. No.: HY-P990651

Target:  

TREM receptor

Research Areas:  

Cancer

PY314 is a humanized antibody targeting TREM2. PY314 binds TREM2 on tumor-associated macrophages, depletes TREM2-high tumor-associated macrophages, reduces pro-tumorigenic M2 macrophage infiltration, increases CD8 + T cell, NK cell, and M1 macrophage infiltration, creates a proinflammatory tumor microenvironment, and promotes antitumor immune responseS. PY314 can be used for the research of platinum-resistant ovarian cancer, advanced solid tumors, breast cancer, and advanced refractory solid tumors .
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