2 Results for "

Pep R54

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Pep R54" in MCE Product Catalog:

Cat. No.: HY-P11011
CAS No.: 2232233-39-3
Synonyms: Pep R54; CXCR4 antagonist Peptide 19
Target:  

CXCR

Research Areas:  

Cancer

Peptide R54 (Pep R54; CXCR4 antagonist peptide 19) is an antagonistic peptide targeting CXCR4 with significant anticancer activity. Peptide R54 inhibits CXCR4-dependent cell migration, epithelial-mesenchymal transition, and lung metastasis development, with better serum stability and higher CXCR4 affinity than the lead compound (IC50=20 nM). Peptide R54 synergizes with anti-PD-1 therapy to exert anti-tumor activity in vivo, enhances granzyme activity, and reduces infiltration of Foxp3 cells. Peptide R54 can be used in the study of colon cancer, ovarian cancer, and melanoma .
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Cat. No.: HY-P11011A
Synonyms: Pep R54 acetate; CXCR4 antagonist Peptide 19 acetate
Target:  

CXCR ERK Akt

Research Areas:  

Cancer

Peptide R54 acetate (Pep R54 acetate) is a CXCR4 antagonist. Peptide R54 acetate inhibits CXCL12-dependent activation of pERK1/2 and pAKT. The combination of Peptide R54 acetate and Nivolumab (HY-P9903) suppresses melanoma growth. Peptide R54 (acetate) is applicable to research related to melanoma and ovarian cancer .
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