1 Result for "

Pfs16

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pfs16" in MCE Product Catalog:

Cat. No.: HY-187123
CAS No.: 1396858-56-2
Target:  

Parasite

Research Areas:  

Infection

DDD01035881 is a Plasmodium falciparum Pfs16 inhibitor, with an EC50 of 130 nM for exflagellation of male gametes of Plasmodium falciparum NF54 gametocytes. DDD01035881 stabilizes mature activated male gametocyte Pfs16, mimics the Pfs16-deficient phenotype, blocks the early formation process of male gametes before DNA replication, inhibits exflagellation, and exhibits male-specific activity with no activity against female gametes or asexual malaria parasite stages. DDD01035881 can be used in malaria-related research .
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