1 Result for "

Phe74

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Phe74" in MCE Product Catalog:

Cat. No.: HY-177063
CAS No.: 296790-70-0
Target:  

Interleukin Related

Research Areas:  

Infection Inflammation/Immunology

IL-6-IN-2 is an interleukin-6 (IL-6) inhibitor. IL-6-IN-2 binds to IL-6 at Lys66, Phe74, Gln175, Ser176, and Arg179 via π-π, π-alkyl, hydrogen bond, and hydrophobic interactions to block IL-6/IL-6R heterocomplex formation. IL-6-IN-2 exhibits low gastrointestinal absorption rate. IL-6-IN-2 can be used for the research of cytokine release syndrome, covid-19 .
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