296790-70-0
Chemical Structure
IL-6-IN-2
- CAS No.: 296790-70-0
- Formula:C26H24N4O3
- Molecular Weight:440.49
IUPAC Name: 4,4'-((5-methylfuran-2-yl)methylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)
InChIKey: XYHXGGRCXFEABW-UHFFFAOYSA-N
SMILES: OC1=C(C(C2=C(N(C3=CC=CC=C3)N=C2C)O)C4=CC=C(C)O4)C(C)=NN1C5=CC=CC=C5
Biological Activity: IL-6-IN-2 is an interleukin-6 (IL-6) inhibitor. IL-6-IN-2 binds to IL-6 at Lys66, Phe74, Gln175, Ser176, and Arg179 via π-π, π-alkyl, hydrogen bond, and hydrophobic interactions to block IL-6/IL-6R heterocomplex formation. IL-6-IN-2 exhibits low gastrointestinal absorption rate. IL-6-IN-2 can be used for the research of cytokine release syndrome, covid-19[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IL-6-IN-2 | 99.95% | IL-6-IN-2 is an interleukin-6 (IL-6) inhibitor. IL-6-IN-2 binds to IL-6 at Lys66, Phe74, Gln175, Ser176, and Arg179 via π-π, π-alkyl, hydrogen bond, and hydrophobic interactions to block IL-6/IL-6R heterocomplex formation. IL-6-IN-2 exhibits low gastrointestinal absorption rate. IL-6-IN-2 can be used for the research of cytokine release syndrome, covid-19. | ||||||||||||||||||||
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Keywords
