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Platelet aggregation-IN-3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176060
    Platelet aggregation-IN-3

    		Histamine Receptor Adrenergic Receptor 5-HT Receptor Cardiovascular Disease Cancer
    Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis .
    Platelet aggregation-IN-3
  • HY-159582
    ACKR3 agonist 1

    		CXCR Cardiovascular Disease
    ACKR3 agonist 1 (compound 27) is a selective ACKR3 agonist (EC50=69 nM, Emax=82%) that inhibits platelet aggregation. ACKR3 agonist 1 is metabolically stable and non-cytotoxic, and has the potential to inhibit platelet-mediated thrombosis .
    ACKR3 agonist 1

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