1029802-21-8
Chemical Structure
Platelet aggregation-IN-3
- CAS No.: 1029802-21-8
- Formula:C13H18ClN3
- Molecular Weight:251.76
InChIKey: SHOKYNWYQLSJLE-UHFFFAOYSA-N
SMILES: C1(NC2=CC=C3C(CCCC3)=C2)=NCCN1.Cl
Biological Activity: Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis[1].
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Platelet aggregation-IN-3 | Platelet aggregation-IN-3 (Compound 5) is a ligand for H2 histamine receptors, α2(A,C)-adrenergic receptors (α2-AR), and 5-HT2(B,C) serotonin receptors. Platelet aggregation-IN-3 can inhibit platelet aggregation induced by ADP and collagen and can also modulate tumour cell-induced platelet aggregation (TCIPA). Platelet aggregation-IN-3 is promising for research of antiplatelet therapy in cardiovascular diseases and the prevention of cancer-related thrombosis and tumour metastasis. | |||||||||||||||||||||
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