5 Results for "

Pomalidomide-C7-COOH

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Pomalidomide-C7-COOH" in MCE Product Catalog:

Cat. No.: HY-133799
CAS No.: 2225940-51-0
Purity:  98.07%
Research Areas:  

Cancer

Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders .
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Cat. No.: HY-P1170
CAS No.: 2703746-32-9
Synonyms: Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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Cat. No.: HY-P10964
CAS No.: 2802416-72-2
Target:  

GHSR

Research Areas:  

Endocrinology

Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .
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Cat. No.: HY-169232
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Cancer

PCC16 chloride is a dual PROTAC degrader targeting DHHC3 and PD-L1, with a DC50 of 0.103 μM for PD-L1 degradation. PCC16 chloride induces DHHC3 degradation via the ubiquitin-proteasome pathway by recruiting the CRBN E3 ubiquitin ligase (E3 ubiquitin ligase). By targeting DHHC3-which is essential for PD-L1 palmitoylation and membrane stability-PCC16 chloride reduces PD-L1 levels, decreases PD-L1 membrane retention time, and impairs its immunosuppressive function. PCC16 chloride enhances anti-tumor immunity by disrupting PD-L1-mediated immunosuppression. PCC16 chloride can be used in the research of immune checkpoint blockade-resistant cancers .
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Cat. No.: HY-P5568
CAS No.: 152835-17-1
Synonyms: RP 71955
Target:  

HIV

Research Areas:  

Infection

RP 71955 is an antimicrobial peptide against HIV-1 .
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