1 Result for "

R-95845

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "R-95845" in MCE Product Catalog:

Referencia número: HY-187616
No. CAS: 163435-77-6
Áreas de investigación:  

Infection Inflammation/Immunology

R-95845 is a non-nucleoside HIV-1 reverse transcriptase (RT) inhibitor. R-95845 is specific to HIV-1 RT and acts as a functionally non-competitive inhibitor with respect to nucleotide incorporation. R-95845 binds to the non-nucleoside inhibitor binding pocket of HIV-1 RT in a butterfly-like conformation, forms hydrogen bonds with Tyr 188 and Val 189, and engages in hydrophobic interactions with surrounding residues. R-95845 can be used in studies related to HIV-1 infection and acquired immunodeficiency syndrome .
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