1 Result for "

R-MDDMA

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "R-MDDMA" in MCE Product Catalog:

Cat. No.: HY-186169
CAS No.: 872679-98-6
Research Areas:  

Neurological Disease

R-MDDMA, 4-methylenedioxymethamphetamine (MDMA) analogue, is a 5-HT2A/5-HT2C receptor modulator. R-MDDMA shows antagonistic activity against 5-HT2A/5-HT2C with IC50 values of 642 and 137 nM, and also shows partial agonist activity with EC50 values of 24.5 and 14.4 nM, but does not activate 5-HT2B receptors. R-MDDMA promotes cortical neuron growth. R-MDDMA facilitates fear extinction learning and produces antidepressant-like effects in preclinical rodent models. R-MDDMA can be used for the researches of post-traumatic stress disorder and depression .
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