1 Result for "

R428-d8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "R428-d8" in MCE Product Catalog:

Art. -Nr.: HY-15150S
Synonyms: R428-d8; BGB324-d8
Bemcentinib-d8 (R428-d8) is the deuterium labeled Bemcentinib (HY-15150). Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer .
loading...
    loading...