1 Result for "

R51211-d3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "R51211-d3" in MCE Product Catalog:

Cat. No.: HY-17514S1
CAS No.: 1217512-35-0
Synonyms: R51211-d3
Itraconazole-d3 (R51211-d3) is the deuterium labeled Itraconazole (HY-17514) . Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.
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