3 Results for "

RET-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "RET-IN-5" in MCE Product Catalog:

Cat. No.: HY-145023
CAS No.: 2725770-20-5
Target:  

RET

Research Areas:  

Cancer

RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC50s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18) .
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Cat. No.: HY-146710
CAS No.: 2259657-48-0
Target:  

RET

Research Areas:  

Cancer

RET-IN-16 is a potent and selective RET inhibitor with IC50s of 3.98 nM, 8.42 nM, 15.05 nM, 7.86 nM, 5.43 nM and 8.86 nM for RET(WT), RET(M918T), RET(V804L), RET(V804M), RET-CCDC6 and RET-KIF5B, respectively. RET-IN-16 has anticancer effects .
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Cat. No.: HY-179308
CAS No.: 2760853-48-1
Research Areas:  

Cancer

RET ligand-5 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC RET Degrader 1 (HY-178964). PROTAC RET Degrader 1 is a potent RET PROTAC degrader with anti-tumor activity .
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