1 Result for "

RMC4745

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RMC4745" in MCE Product Catalog:

Cat. No.: HY-150108
CAS No.: 2250059-80-2
Target:  

mTOR Apoptosis Caspase

Research Areas:  

Cancer

RMC-4745 is a selective dual-site inhibitor of mTORC1, with a selectivity of 35 times for mTORC1 and mTORC2. RMC-4745 inhibits the proliferation of MCF-7 cells and upregulates Caspase-3/7 activity to induce cell apoptosis. RMC-4745 does not cause the upregulation of HER3 due to the inhibition of mTORC2. RMC-4745 can be used for the study of breast cancer .
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