1 Result for "

RO 16-6491

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RO 16-6491" in MCE Product Catalog:

Cat. No.: HY-W205529
CAS No.: 87235-61-8
Target:  

Fluorescent Dye

Research Areas:  

Neurological Disease

RO 16-6491 Free base is a selective, reversible inhibitor of monoamine oxidase type B (MAO-B), exhibiting high affinity and specificity for binding sites in human frontal cortex mitochondria and platelet membranes. RO 16-6491 demonstrates a fast dissociation of bound radioactivity at 20 degrees C, indicating its dynamic binding properties. RO 16-6491 also acts as a substrate for MAO-B, suggesting that its oxidation may produce a stable intermediate responsible for its potent inhibitory effects. RO 16-6491 serves as an excellent radioligand probe for investigating the regional tissue distribution of MAO-B in various physiological and pathological states.
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