1 Result for "

RO4988546

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RO4988546" in MCE Product Catalog:

Cat. No.: HY-129274
CAS No.: 911114-85-7
Target:  

mGluR

Research Areas:  

Neurological Disease

RO4988546 is a negative allosteric modulator (NAM) that targets metabotropic glutamate receptors 2 and 3 (mGlu2, mGlu3). RO4988546 can reduce the binding of [ 3h]-LY354740 at the positive binding site, while affecting the receptor's G protein coupling and intracellular signaling. RO4988546 can be used in the development of antidepressants and cognitive enhancers .
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