1 Result for "

RP6685

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RP6685" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-151462
CAS No.: 2832047-80-8
Purity:  99.88%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

RP-6685 is a potent, selective and orally active DNA polymerase theta (Polθ) inhibitor with an IC50 value of 5.8 nM (PicoGreen assay). RP-6685 shows antitumor efficacy in mouse tumor xenograft model . RP-6685 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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