1 Result for "

RV1729

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RV1729" in MCE Product Catalog:

Referencia número: HY-106006
No. CAS: 1293915-42-0
Target:  

PI3K

Áreas de investigación:  

Others Inflammation/Immunology

RV-1729 is an inhibitor of the phosphatidylinositol 3-kinase-δ (PI3Kδ). RV-1729 identifies inhibition of the PI3K isotype by quantifying the release of phosphatidylinositol 3,4, 5-triphosphate (PIP3) (IC50=12 nM), showing twice the selectivity for PI3Kδ relative to PI3Kγ. RV-1729 is also 16 times more selective to PI3Kα. RV-1729 regulates immune and inflammatory responses by inhibiting PI3Kδ. RV-1729 can be used in studies of asthma and chronic obstructive pulmonary disease (COPD) .
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