1 Result for "

Rendomab-B49

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Rendomab-B49" in MCE Product Catalog:

Cat. No.: HY-P991964
Synonyms: Rendomab-B49

Target:  

Endothelin Receptor

Research Areas:  

Cancer

Rendomab B4 (Rendomab-B49) is a monoclonal antibody targeting ETB. Rendomab B4 preferentially binds to ETB in the active conformational state and exhibits selectivity for ETB on melanoma cells. Rendomab B4 inhibits the G protein-dependent phospholipase C (PLC) pathway, blocks ET-3-induced Gαi/o-mediated inhibition of adenylate cyclase, and does not affect the activation of the ERK1/2 pathway. Rendomab B4 is applicable to melanoma-related research .
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