1 Result for "

SAR442257

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SAR442257" in MCE Product Catalog:

Cat. No.: HY-P991183

Target:  

CD28 CD38 CD3

Research Areas:  

Cancer

SAR-442257 is a trispecific T-cell engager and monoclonal antibody that binds to CD38, CD3 and CD28. SAR-442257 can target and bind to CD3 and CD28 on T cells, as well as CD38 expressed on tumor cells. SAR-442257 mediates T-cell activation, enhances T-cell activity, induces T-cell degranulation, and drives cytotoxicity against multiple myeloma cells. SAR-442257 functions via CD38 expression, and its in vitro activity correlates with CD38 expression on the surface of multiple myeloma cells. SAR-442257 can be used in studies related to multiple myeloma and relapsed/refractory multiple myeloma .
loading...
    loading...