1 Result for "

SERT-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SERT-IN-4" in MCE Product Catalog:

Cat. No.: HY-184011
SERT-IN-4 is a brain-penetrant and orally active SERT inhibitor and ERβ agonist with human SERT IC50 of 16.92 nM and human ERβ EC50 of 3.66 nM. SERT-IN-4 inhibits SERT-mediated substrate transport, increases hippocampal serotonin levels, modulates p-CREB and BDNF expression.SERT-IN-4 reduces immobility in CUMS mice, improves social interaction and reduces inactivity in CSDS mice.SERT-IN-4 can be used for the research of major depressive disorder .
loading...
    loading...