2 Results for "

SGLT2-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SGLT2-IN-4" in MCE Product Catalog:

Cat. No.: HY-180201
CAS No.: 1061314-92-8
Target:  

SGLT

Research Areas:  

Metabolic Disease

SGLT2-IN-4 (Compound 1) is a selective and orally active sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor. SGLT2-IN-4 can increase the proportion of protein α-helix and enhance the stability of the SGLT2-D201A mutant. SGLT2-IN-4 can be used for the research of type 2 diabetes .
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Cat. No.: HY-178734
CAS No.: 1800115-22-3
Target:  

SGLT

Research Areas:  

Metabolic Disease

Janagliflozin is orally active and highly selective sodium-glucose cotransporter 2 (SGLT2) inhibitor (IC50=0.0058 μM for SGLT2 and 4.802 μM for SGLT1). Janagliflozin inhibits SGLT2 in the proximal renal tubules, reducing glucose reabsorption and promoting urinary glucose excretion (UGE) to lower blood glucose levels. Janagliflozin is promising for research of type 2 diabetes mellitus .
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