1 Result for "

SHY867

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHY867" in MCE Product Catalog:

Referencia número: HY-178211
No. CAS: 2446484-96-2
Target:  

Ras MEK ERK Akt

Áreas de investigación:  

Cancer

SHY-867 is a pan RAS inhibitor. SHY-867 effectively prevents the binding of K-Ras proteins and other members of the Ras superfamily of small GTPases with EC50 values of 0.5-3 μM. SHY-867 effectively inhibits the phosphorylation of MEK, ERK1/2, and AKT downstream of K-Ras. SHY-867 inhibits the formation of the Ras-GTP activity complex. SHY-867 can be used to the studies of pancreatic cancer and non-small cell lung cancer .
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