1 Result for "

SKLB188

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SKLB188" in MCE Product Catalog:

Cat. No.: HY-120412
CAS No.: 1350545-09-3
Target:  

EGFR Apoptosis

Research Areas:  

Cancer

SKLB188 is an orally active and potent epidermal growth factor receptor (EGFR) inhibitor (IC50=5 nM). SKLB188 suppresses MEK/Erk and Akt/mTOR signaling pathways to inhibit head and neck squamous cell carcinoma (HNSCC) proliferation and induce caspase-dependent apoptosis. SKLB188 is promising for research of EGFR-overexpressing solid tumors .
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